Condition: Parkinson’s Disease


Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson’s disease

Please use this link to access this publication. Abstract Medications that improve pain threshold can be useful in the pharmacotherapy of Parkinson’s disease (PD). Pain is a prevalent PD’s non-motor symptom with a higher…

Cannabidiol exerts protective effects in an in vitro model of Parkinson’s disease activating AKT/mTOR pathway

Please use this link to access this publication. Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the degeneration of the nigrostriatal dopaminergic pathway with loss of substantia nigra pars compacta neurons…

Cannabis Dopaminergic Effects Induce Hallucinations in a Patient with Parkinson’s Disease

Abstract Cannabis products that contain the tetrahydrocannabinol (THC) cannabinoid are emerging as promising therapeutic agents for the treatment of medical conditions such as chronic pain. THC elicits psychoactive effects through…

The Role of Cannabidiol in Neurological Disorders

Abstract Cannabis has been used for both recreational and medicinal purposes for more than 4 millennia. Cannabis has been studied in various medical disorders including neurological disorders. There are well-known…

Cannabis in Parkinson’s Disease: The Patients’ View

Please use this link to access this publication. Abstract: Background: Little is known about the patients’ view on treatment with medical cannabis (MC) for Parkinson’s disease (PD). Objective:To assess the PD…

A single oral dose of cannabidiol did not reduce upper limb tremor in patients with essential tremor

Please use this link to access this publication. Abstract Essential tremor (ET) is a common clinical syndrome characterized by action tremors affecting both upper limbs that can compromise manual tasks’…

Potential role of cannabidiol in Parkinson’s disease by targeting the WNT/β-catenin pathway, oxidative stress and inflammation

Abstract Parkinson’s disease (PD) is a major neurodegenerative disease (ND), presenting a progressive degeneration of the nervous system characterized by a loss of dopamine in the substantia nigra pars compacta….

Neuroprotective and Symptomatic Effects of Cannabidiol in an Animal Model of Parkinson’s Disease

Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia Nigra pars compacta, leading to classical PD motor symptoms. Current therapies are…

Emerging potential of cannabidiol in reversing proteinopathies

Please use this link to access this publication. Abstract The aberrant accumulation of disease-specific protein aggregates accompanying cognitive decline is a pathological hallmark of age-associated neurological disorders, also termed as…

Cannabidiol has therapeutic potential for myofascial pain in female and male parkinsonian rats

Please use this link to access this publication. Abstract The musculoskeletal orofacial pain is a complex symptom of Parkinson’s disease (PD) resulting in stomatognathic system dysfunctions aggravated by the disease…