Abstract For thousands of years, Cannabis sativa has been utilized as a medicine and for recreational and spiritual purposes. Phytocannabinoids are a family of compounds that are found in the cannabis plant,…
Keyword: Cannabinoid receptor 1 (CB1)
Association of Cannabis Use During Adolescence With Neurodevelopment
Abstract Importance Animal studies have shown that the adolescent brain is sensitive to disruptions in endocannabinoid signaling, resulting in altered neurodevelopment and lasting behavioral effects. However, few studies have investigated ties…
Adverse Effects of Recreational and Medical Cannabis
Abstract Purpose of Review: This comprehensive review discusses the adverse effects known today about marijuana, for either medical or recreational use. It reviews the role of cannabis in the treatment…
Selective alterations of endocannabinoid system genes expression in obsessive compulsive disorder
Abstract Obsessive Compulsive Disorder (OCD) is listed as one of the top 10 most disabling neuropsychiatric conditions in the world. The neurobiology of OCD has not been completely understood and…
Cannabinoids and Their Receptors in Skin Diseases
Abstract The therapeutic application of cannabinoids has gained traction in recent years. Cannabinoids interact with the human endocannabinoid system in the skin. A large body of research indicates that cannabinoids…
Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Abstract Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS). Receptors from the…
Cannabis effectiveness on immunologic potency of pulmonary contagion
Please use this link to access this publication. Abstract Respiratory illnesses and its repercussions are becoming more prevalent worldwide. It is necessary to research both innovative treatment and preventative techniques….
How important are sex differences in cannabinoid action?
Abstract In humans as in animals, males and females are dissimilar in their genetic and hormonally driven behaviour; they process information differently, perceive experience and emotions in different ways, display…
Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists
Please use this link to access this publication. Abstract Δ9-Tetrahydrocannabinol (Δ9-THC), the principal psychoactive constituent of the Cannabis sativa plant, and other agonists at the central cannabinoid (CB1) receptor may induce characteristic…
Hypothalamic cannabinoid signaling: Consequences for eating behavior
Abstract In parallel to the legalization of cannabis for both medicinal and recreational purposes, cannabinoid use has steadily increased over the last decade in the United States. Cannabinoids, such as…